Targeting the NLRP3 inflammasome abrogates cardiotoxicity of immune checkpoint blockers
Background Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of many malignant tumors.However, ICI-induced hyper-immune activation causes cardiotoxicity.Traditional treatments such as glucocorticoids and immunosuppressants have limited effectiveness and may even accelerate tumor growth.This study baseball scoreboards for sale ai